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izvor podataka: crosbi

Thyroid hormone levels are associated with metabolic components: a cross-sectional study (CROSBI ID 291028)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Punda, Ante ; Škrabić, Veselin ; Torlak, Vesela ; Gunjača, Ivana ; Boraska Perica, Vesna ; Kolčić, Ivana ; Polašek, Ozren ; Hayward, Caroline ; Zemunik, Tatijana ; Matana, Antonela Thyroid hormone levels are associated with metabolic components: a cross-sectional study // Croatian medical journal, 61 (2020), 3; 230-238. doi: 10.3325/cmj.2020.61.230

Podaci o odgovornosti

Punda, Ante ; Škrabić, Veselin ; Torlak, Vesela ; Gunjača, Ivana ; Boraska Perica, Vesna ; Kolčić, Ivana ; Polašek, Ozren ; Hayward, Caroline ; Zemunik, Tatijana ; Matana, Antonela

engleski

Thyroid hormone levels are associated with metabolic components: a cross-sectional study

Aim To analyze the association of thyroid function and hormone levels with metabolic syndrome (MetS) and its components. Methods This cross-sectional population-based study involved 2183 Croatian individuals with no history of thyroid disease, hypertension, diabetes, and hyperlipidemia. MetS was diagnosed according to the National Cholesterol Education Program’s Adult Treatment Panel III criteria. Results We found no association between thyroid function groups and the prevalence of MetS and its components. Clinically hypothyroid participants showed significantly higher triceps skinfold measurements than subclinically hypothyroid and euthyroid participants. Furthermore, clinically hypothyroid participants had higher abdominal skinfold thickness than subclinically hypothyroid participants. Otherwise, suprailiac and abdominal skinfold measurements were higher in the subclinically and clinically hyperthyroid group of participants compared with euthyroid and subclinically hypothyroid participants. A strong positive association of thyroid-stimulating hormone (TSH) and strong negative association of free triiodothyronine (fT3) and free thyroxine (fT4) levels with HOMA-IR and cholesterol levels were found. Furthermore, the fT4 level also showed a strong negative association with HDL and triceps skinfold thickness. Conclusions This study supports the standing that TSH, fT3, and fT4 levels are important variables to determine the association of thyroid function with MetS.

thyroid hormones ; metabolic components

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Podaci o izdanju

61 (3)

2020.

230-238

objavljeno

0353-9504

1332-8166

10.3325/cmj.2020.61.230

Povezanost rada

Temeljne medicinske znanosti

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