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izvor podataka: crosbi

The Listeriosis Triangle: Pathogen, Host and the Environment (CROSBI ID 185318)

Prilog u časopisu | izvorni znanstveni rad

Abram, Maja ; Bubonja-Šonje, Marina ; Mihelčić, Mirna ; Vučković, Darinka ; Mustać, Elvira The Listeriosis Triangle: Pathogen, Host and the Environment // Sanamed, 7 (2012), 1; 37-42

Podaci o odgovornosti

Abram, Maja ; Bubonja-Šonje, Marina ; Mihelčić, Mirna ; Vučković, Darinka ; Mustać, Elvira

engleski

The Listeriosis Triangle: Pathogen, Host and the Environment

Listeria monocytogenes is a foodborne pathogen well known for its adaptability to diverse envirnoment and host niches and its high fatality rate among infected immunocompromised populations. Infection in the immunocompetent host occurs but risk factors for the disease primarily points to abnormalities in cell-mediated and innate immunity as major predispositions to listeriosis. After ingestion of contaminated food, this pathoge is able to cross the intestinal, blood-brain and placental barrier and leads to gastroenteritis, meningitis and maternofetal infections which may result in abortion and spontaneous stillbirth. Deispite the extensive use of this bacterium in the study of cell-mediated immunity and intracellular growth, our understanding of the host, pathogen and environmental factor that impact the pathogenesis of listeriosis is still inclomplete. This review will summarize current knowledge, including our own efforts, about pathogen, host and environmental factors that influence, and contribute to the pathogenesis of Listeria monocytogenes infection.

Listeria monocytogenes ; listeriosis ; mouse model ; Acanthamoeba castellanii

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Podaci o izdanju

7 (1)

2012.

37-42

objavljeno

1452-662X

2217-8171

Povezanost rada

Temeljne medicinske znanosti, Kliničke medicinske znanosti

Poveznice