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Marko Košiček
(305082)

 
 
 
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  Izvorni znanstveni i pregledni radovi u CC časopisima
 

1. Košiček, Marko; Gudelj, Ivan; Horvatić, Anita; Jović, Tanja; Vučković, Frano; Lauc, Gordan; Hećimović, Silva.
N-glycome of the lysosomal glycocalyx is altered in Niemann-Pick Type C disease model cells. // Molecular & cellular proteomics. 17 (2018) , 4; 631-642 (članak, znanstveni). URL link to workURL link to work

2. Košiček, Marko; Wunderlich, Patrick; Walter, Jochen; Hećimović, Silva.
GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells. // Biochemical and biophysical research communications. 450 (2014) , 1; 160-165 (članak, znanstveni). URL link to workURL link to work

3. Košiček, Marko; Hećimović, Silva.
Phospholipids and Alzheimer’s disease: alterations, mechanisms and potential biomarkers. // International journal of molecular sciences. 14 (2013) , 1; 1310-1322 (pregledni rad, znanstveni). URL link to workURL link to work

4. Košiček, Marko; Zetterberg, Henrik; Andreasen, Niels; Peter-Katalinić, Jasna; Hećimović, Silva.
Elevated cerebrospinal fluid sphingomyelin levels in prodromal Alzheimer’s disease. // Neuroscience letters. 516 (2012) , 2; 302-305 (članak, znanstveni). URL link to workURL link to work

5. Malnar, Martina; Košiček, Marko; Bene, Raphael; Petek Tarnik, Iva; Pavelin, Sanda; Babić, Ivana; Brajenović-Milić, Bojana; Hećimović, Hrvoje; Titlić, Marina; Trkanjec, Zlatko; Demarin, Vida; Hećimović, Silva.
Use of cerebrospinal fluid biomarker analysis and apolipoprotein E genotyping for improving Alzheimer’s disease diagnosis in a non-specialized setting. // Acta neurobiologiae experimentalis. 72 (2012) , 3; 264-271 (članak, znanstveni). URL link to work

6. Malnar, Martina; Košiček, Marko; Lisica, Ana; Posavec, Melanija; Krolo, Ana; Njavro, Jasenka; Omerbašić, Damir; Tahirović, Sabina; Hećimović, Silva.
Cholesterol-depletion corrects APP and BACE1 misstrafficking in NPC1-deficient cells. // Biochimica et biophysica acta-molecular basis of disease. 1822 (2012) , 8; 1270-1283 (članak, znanstveni). URL link to workURL link to work

7. Mattsson, Niklas; Olsson, Maria; Gustavsson, Mikael K.; Košiček, Marko; Malnar, Martina; Månsson, Jan-Eric; Blomqvist, Maria; Gobom, Johan; Andreasson, Ulf; Brinkmalm, Gunnar; Vite, Charles; Hećimović, Silva; Hastings, Caroline; Blennow, Kaj; Zetterberg, Henrik; Portelius, Erik.
Amyloid-β metabolism in Niemann-Pick C disease models and patients. // Metabolic brain disease. 27 (2012) , 4; 573-585 (članak, znanstveni). URL link to workURL link to work

8. von Einem, Bjorn; Weber, Petra; Wagner, Michael; Malnar, Martina; Košiček, Marko; Hećimović, Silva; von Arnim, Christine; Schneckenburger, Herbert.
Cholesterol dependent energy transfer between fluorescent proteins - insights into protein proximity of APP and BACE1 in different membranes in Niemann-Pick type C disease cells. // International journal of molecular sciences. 13 (2012) , 12; 15801-15812 (članak, znanstveni). URL link to workURL link to work

9. Košiček, Marko; Kirsch, Stefan; Bene, Raphael; Trkanjec, Zlatko; Titlić, Marina; Bindila, Laura; Peter-Katalinić, Jasna; Hećimović, Silva.
Nano-HPLC-MS analysis of phospholipids in cerebrospinal fluid of Alzheimer’s disease patients–a pilot study. // Analytical and bioanalytical chemistry. 398 (2010) , 7/8; 2929-2937 (članak, znanstveni). prilozen text radaURL link to workURL link to work

10. Košiček, Marko; Malnar, Martina; Goate, Alison; Hećimović, Silva.
Cholesterol accumulation in Niemann Pick type C (NPC) model cells causes a shift in APP localization to lipid rafts. // Biochemical and biophysical research communications. 393 (2010) , 3; 404-409 (članak, znanstveni). URL link to workURL link to work

11. Malnar, Martina; Košiček, Marko; Mitterreiter, Stefan; Omerbašić, Damir; Lichtenthaler, Stefan F.; Goate, Alison; Hećimović, Silva.
Niemann Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the β-secretase pathway. // Biochimica et biophysica acta : molecular basis of disease. 1802 (2010) , 7/8; 682-691 (članak, znanstveni). prilozen text radaURL link to workURL link to work
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  Znanstveni radovi u drugim časopisima
 

1. Cermak, Stjepko; Kosicek, Marko; Mladenovic-Djordjevic, Aleksandra; Smiljanic, Kosara; Kanazir, Selma; Hecimovic, Silva.
Loss of Cathepsin B and L Leads to Lysosomal Dysfunction, NPC-Like Cholesterol Sequestration and Accumulation of the Key Alzheimer's Proteins. // PLoS One. 11 (2016) , 11; e0167428-1-e0167428-17 (članak, znanstveni). URL link to workURL link to work

2. Štefulj, Jasminka; Perić, Maja; Malnar, Martina; Košiček, Marko; Schweinzer, Cornelia; Živković, Jelena; Scholler, Monika; Panzenboeck, Ute; Hećimović, Silva.
Pharmacological activation of LXRs decreases amyloid-β levels in Niemann-Pick type C model cells. // Current pharmaceutical biotechnology. 14 (2013) , 6; 582-593 (članak, znanstveni). URL link to work

3. Malnar, Martina; Košiček, Marko; Hećimović, Silva.
Alzheimerova bolest: od molekularnog mehanizma do rane dijagnoze. // Medicina : glasilo Hrvatskoga liječničkoga zbora, Podružnica Rijeka. 45 (2009) , 3; 234-243 (pregledni rad, znanstveni). URL link to work
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  Kongresno priopćenje (sažeci) u CC časopisu
 

1. Kosicek, Marko; Hecimovic, Silva; Kirsch, Stephan; Bene, Raphael; Trkanjec, Zlatko; Titlic, Marina; Bindila, Laura; Peter-Katalinic, Jasna.
Sphingomyelin is elevated in cerebrospinal fluid of Alzheimer's disease patients // Alzheimer's and Dementia.
New York : Elsevier, 2011. 140-140 (poster,međunarodna recenzija,sažetak,znanstveni). URL link to work

2. Stefulj, Jasminka; Malnar, Martina; Schweinzer, Cornelia; Kosicek, Marko; Zivkovic, Jelena; Panzenboeck, Ute; Hecimovic, Silva.
The impacts of LXR ligand TO901317 on amyloid-β levels and cholesterol metabolism in Niemann-Pick type C (NPC) model cells // Alzheimer's and Dementia.
New York : Elsevier, 2011. e72-e72 (poster,međunarodna recenzija,sažetak,znanstveni). URL link to work

3. Košiček, Marko; Hećimović, Silva.
Cholesterol accumulation in NPC fibroblasts leads to lipid raft comartmentalization of APP and C99 // Alzheimer's and Dementia 5 (Suppl.1).
New York : Elsevier, 2009. 225-225 (poster,međunarodna recenzija,sažetak,znanstveni).

4. Lisica, Ana; Krolo, Ana; Malnar, Martina; Košiček, Marko; Hećimović, Silva.
Loss of NPC1 leads to decreased expression of APP at the cell surface and alters APP distribution within endosome compartments // Alzheimer's and Dementia 5 (Suppl. 1).
New York : Elsevier, 2009. 301-301 (poster,međunarodna recenzija,sažetak,znanstveni).

5. Košiček, Marko; Goate, Alison; Hećimović, Silva.
Increased Formation Of Amyloid-beta Peptide In CHO NPC1-null Cells Does Not Involve Lipid Rafts // Alzheimer's & Dementia 4 (Suppl 2).
New York : Elsevier, 2008. T350-T350 (poster,međunarodna recenzija,sažetak,znanstveni).

6. Malnar, Martina; Košiček, Marko; Goate, Alison; Hećimović, Silva.
Increased Abeta Formation In CHO NPC1-null Cells Is Not Directly Related To Cholesterol Levels // Alzheimer's & Dementia 4 (Suppl 2).
New York : Elsevier, 2008. T349-T349 (poster,međunarodna recenzija,sažetak,znanstveni).
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  Kongresno priopćenje (sažeci) u ostalim časopisima
 

1. Hećimović, Silva; Malnar, Martina; Košiček, Marko; Čulić, Vida; Lozić, Bernarda; Barišić, Ingeborg.
The fragile X syndrome : a Croatian perspective // Abstracts of the 8th Balkan Meetng on Human Genetics ; u: Paediatria Croatica, 53 (2009) (S2).
2009. 56-56 (predavanje,međunarodna recenzija,sažetak,znanstveni).

2. Malnar, Martina; Petek Tarnik, Iva; Košiček, Marko; Pavelin, Sanda; Titlić, Marina; Trkanjec, Zlatko; Demarin, Vida; Hećimović, Silva.
Cerebrospinal fluid biomarker analysis in Alzheimer's disease : a pilot study in Croatia // Abstracts of trhe 8th Balkan Meeting on Human Genetics ; u: Paediatria Croatica 53 (2009) (S2).
2009. 69-69 (poster,međunarodna recenzija,sažetak,znanstveni).

3. Hećimović, Silva; Malnar, Martina; Košiček, Marko; Petek Tarnik, Iva; Trkanjec, Zlatko; Titlić, Marina; Demarin, Vida; Goate, Alison.
Amyloid-β : from molecular biology to clinical practice // 4. hrvatski kongres o Alzheimerovoj bolesti s međunarodnim sudjelovanjem : knjiga sažetaka ; u: Neurologia Croatica 57 (2008) (S4).
2008. 16-17 (predavanje,domaća recenzija,sažetak,znanstveni).

4. Košiček, Marko; Goate, Alison; Katušić Hećimović, Silva.
The role of lipid rafts on app processing and Amyloid-β formation // 4. hrvatski kongres o Alzheimerovoj bolesti s međunarodnim sudjelovanjem : knjiga sažetaka ; u: Neurologia Croatica 57 (2008) (S4).
2008. 70-70 (poster,domaća recenzija,sažetak,znanstveni).

5. Malnar, Martina; Košiček, Marko; Goate, Alison; Hećimović, Silva.
The cholesterol-effect on amyloid-β formation upon NCP1 dysfunction involves altered APP localization // 4. hrvatski kongres o Alzheimerovoj bolesti s međunarodnim sudjelovanjem : knjiga sažetaka ; u: Neurologia Croatica 57 (2008) (S4).
2008. 71-71 (poster,domaća recenzija,sažetak,znanstveni).
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  Sažeci u zbornicima skupova
 

1. Blažeković, Antonela; Gotovac Jerčić, Kristina; Košiček, Marko; Malnar, Martina; Outeiro, Tiago; Hećimović, Silva; Borovečki, Fran.
GENETIC MECHANISMS OF LYSOSOMAL DYSFUNCTION IN PARKINSON’S DISEASE – the effect of novel variants on alpha- synuclein accumulation // SfN 47th Annual Meeting.
2017. (poster,međunarodna recenzija,sažetak,znanstveni).

2. Košiček, Marko; Jović, Tanja; Hećimović, Silva.
Isolation and characterization of lysosomes in NPC model cells // FEBS Advanced lecture Course ; 360o Lysosome: from structure to genomics, from function to disease / Zihni Onur Uygun (ur.).
Izmir : Ege University Publishing House, 2014. 80-80 (poster,sažetak,znanstveni).

3. Hećimović, Silva; Košiček, Marko; Malnar, Martina.
Cholesterol Levels Modulate Endosomal Localization of BACE1 // .
(poster,sažetak,znanstveni).

4. von Arnim, Christine; von Einem, Bjorn; Weber, Petra; Wagner, Michael; Malnar, Martina; Košiček, Marko; Hećimović, Silva; Schneckenburger, Herbert.
Protein Proximity of APP and BACE1 and Membrane Stiffness Is Altered in Different Membranes in Niemann-Pick Type C Disease Cells // .
(poster,sažetak,znanstveni).

5. Košiček, Marko; Bindila, Laura; Peter-Katalinić, Jasna; Hećimović, Silva.
Cerebrospinal fluid lipidomics in Alzheimer's disease // FEBS/IUBMB workshop : Eukaryotic lipids : Treasure of Regulatory Information : Abstracts.
(predavanje,međunarodna recenzija,sažetak,znanstveni).

6. Krolo, Ana; Lisica, Ana; Malnar, Martina; Košiček, Marko; Hećimović, Silva.
Accumulation of cholesterol in Niemann Pick type C cells alters APP distribution within endosome compartments // FEBS Advanced Course: Lipid signaling and disease 2009.
(poster,međunarodna recenzija,sažetak,znanstveni).

7. Malnar, Martina; Košiček, Marko; Hećimovicć, Silva.
Cholesterol accumulation upon NPC1 dysfunction alters APP expression at the cell surface leading to its increased processing through the β-secretase pathway // FEBS Advanced Course: Lipid signaling and disease 2009.
(poster,međunarodna recenzija,sažetak,znanstveni).

8. Posavec, Melanija; Krolo, Ana; Omerbašić, Damir; Lisica, Ana; Malnar, Martina; Košiček, Marko; Hećimović, Silva.
Cholesterol accumulation upon NPC1 dysfunction alters endosomal compartmentalization of β-amyloid precursor protein // EMBO Young Scientists Forum 2009.
(poster,međunarodna recenzija,sažetak,znanstveni).

9. Hećimović, Silva; Omerbašić, Damir; Posavec, Melanija; Malnar, Martina; Košiček, Marko; Goate, Alison.
Cholesterol accumulation upon NPC1 dysfunction alters trafficking of APP/C99 // The 2008 Golgi Meeting.
2008. 105-105 (poster,međunarodna recenzija,sažetak,znanstveni).

10. Košiček, Marko; Goate, Alison; Hećimović, Silva.
The role of lipid rafts on app processing in NPC1-null cells // Workshop Adenoviruses Basic to Gene Therapy : programme and abstracts / Majhen, Dragomira ; Ambriović Ristov, Andreja (ur.).
Zagreb : Croatian Microbiological Society, 2008. 18-18 (predavanje,domaća recenzija,sažetak,znanstveni).

11. Malnar, Martina; Košiček, Marko; Goate, Alison; Hećimović Silva.
Cholesterol effect on formation of amyloid-b peptide upon NPC1 dysfunction // Workshop Adenoviruses Basic to Gene Therapy : programme and abstracts / Majhen, Dragomira ; Ambriović Ristov, Andreja (ur.).
Zagreb : Croatian Microbiological Society, 2008. 29-29 (poster,domaća recenzija,sažetak,znanstveni).

12. Šahnić, Damir; Majić, Željka; Smrečki-Lolić, Neven; Košiček, Marko; Popović, Zora.
Priprava i svojstva kompleksa odabranih metala s biološki aktivnim spojevima // XIX. hrvatski skup kemičara i kemijskih inženjera : Knjiga sažetaka = Book of abstracts / Rapić, Vladimir ; Rogošić, Marko (ur.).
Zagreb : Hrvatsko društvo kemijskih inženjera i tehnologa : Hrvatsko kemijsko društvo, 2005. 54-54-54 (poster,sažetak,znanstveni).
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  Neobjavljena sudjelovanja na skupovima
 

1. Malnar, Martina; Košiček, Marko; Mitterreiter, Stefan; Lichtenthaler, Stefan F.; Hećimović, Silva.
Cholesterol accumulation in Niemann-Pick type C cells favors APP processing by β-secretase and causes altered endocytic trafficking of BACE1 // .
(poster,neobjavljeni rad,znanstveni). URL link to work

2. Katušić Hećimović, Silva; Malnar, Martina; Košiček, Marko.
Niemann-Pick type C disease – a model to study the role of cholesterol in the pathogenesis of Alzheimer's disease // .
(poster,međunarodna recenzija,neobjavljeni rad,znanstveni).

3. Malnar, Martina; Košiček, Marko; Tahirović, Sabina; Katušić Hećimović Silva.
Cholesterol levels modulate trafficking of APP and BACE1 in Niemann-Pick type C cells // .
(poster,neobjavljeni rad,znanstveni).

4. Malnar, Martina; Košiček, Marko; Tahirović, Sabina; Katušić Hećimović, Silva.
Cholesterol levels modulate trafficking of APP and BACE1 in Niemann-Pick type C cells // .
(pozvano predavanje,neobjavljeni rad,znanstveni).

5. Košiček, Marko; Goate, Alison; Hećimović, Silva.
The role of lipid rafts on app processing and amyloid-beta formation // 3rd Summer Course on Mass Spectrometry in Biotechnology and Medicine 2009.
(poster,neobjavljeni rad,znanstveni).
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  Disertacije
 

1. Košiček, Marko.
Utjecaj lipida na patogenezu Alzheimerove bolesti - od molekularnog mehanizma do biomarkera bolesti / doktorska disertacija.
Zagreb : Prirodoslovno-matematički fakultet, 16.05. 2013, 97 + XXXII str. Voditelj: Katušić Hećimović, Silva.
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  Diplomski radovi
 

1. Košiček, Marko.
Utjecaj lipidnih splavi i kolesterola na metabolizam proteina APP / diplomski rad.
Zagreb : Prirodoslovno-matematički, 27.09. 2007., 39 str. Voditelj: Weygand-Đurašević, Ivana.
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  Vođenje disertacija, magistarskih i diplomskih radova
 

1. Kular, Dolores.
Utjecaj nakupljanja kolesterola na metabolizam proteina APLP1 i APLP2 u stanicama CHO NPC1-null / završni rad - diplomski/integralni studij.
Zagreb : Prirodoslovno-matematički fakultet, 14.07. 2011., 44 str. Voditelj: Silva Katušić Hećimović.

2. Njavro, Jasenka.
Utjecaj nakupljanja kolesterola u stanicama CHO NPC1-/- na smještaj proteina BACE1 u organelima endocitoznog puta / završni rad - diplomski/integralni studij.
Zagreb : Prirodoslovno-matematički fakultet, 22.09. 2011., 47 str. Voditelj: Silva Katušić Hećimović.
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