Atrazine exposure decreases cell proliferation in Chinese Hamster Ovary (CHO-K1) cell line (CROSBI ID 118493)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Kmetič, Ivana ; Gaurina Srček, Višnja ; Slivac, Igor ; Šimić, Branimir ; Kniewald, Zlatko ; Kniewald, Jasna
engleski
Atrazine exposure decreases cell proliferation in Chinese Hamster Ovary (CHO-K1) cell line
The aim of this study was to determine the toxic effect of atrazine at the ovarian cellular level. Chinese Hamster Ovary (CHO-K1) cell line was used to evaluate the degree of in vitro atrazine cytotoxicity and the morphological changes were followed during the cell death. Application of four bioassays confirmed that atrazine decreases ovarian cell proliferation and IC50 were determined with each assay after 72 h of exposure. The level of apoptosis in atrazine treated cells was low.
atrazine; CHO-K1 cells; IC50 values; apoptosis
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Podaci o izdanju
81 (2)
2008.
205-209
objavljeno
0007-4861
10.1007/s00128-008-9425-6
