The relationship of sodium and calcium intake with bone mass in postmenopausal women (CROSBI ID 520134)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Cvijetić, Selma ; Blanuša, Maja ; Colić Barić, Irena ; Ilich, Jasminka
engleski
The relationship of sodium and calcium intake with bone mass in postmenopausal women
The relationship between calcium and sodium metabolism is well known. High sodium intake can accelerate calcium excretion and hypercalciuria is risk factor for osteoporosis. Aim: to analyze the relationship of sodium and calcium intake and excretion with bone mineral density(BM D) in postmenopausal women. Subjects and Methods: 120 postmenopausal women participated in the study. The mean age was 59.9 + 7.2 years and the mean age after menopause was 10.8 + 7.4 years. Bone mineral density(BMD) was measured, using dual energy X-ray absorptiometry, in spine, proximal femur, radius and total body. Spot urine samples were analyzed for calcium, magnesium, sodium and potassium. The values obtained for metals were expressed as ratios to creatinine (mg/g creatinine). Calcium and sodium intake were assessed using three-dayd ietary records. Results: Most women had normal BMD in all measured sites. Osteoporosis (T score < )2.5) was most common in radius (cortical bone) (15.9%) and in spine (14.2%), while the greatest number of women had normal BMD in total body(73.2 %). There were no di.erences in obtained concentrations of elements between subjects with and without osteoporosis. The significant correlation (p < 0.0001) between calcium and sodium in urine was determined. Subjects with osteoporosis had signi.cant correlation between urinarycalci um and BMD (p < 0.05). The mean calcium intake was 809.8 + 348.5 mg/dayand the mean sodium intake was 5335.6 + 1650.6 mg/day, with no signi.cant di.erence between subjects with and without osteoporosis. Using regression analysis and after controlling for age and anthropometry, we founded that potassium in urine was the only significant predictor of bone mass (p< 0.05). There was no significant relationship between sodium intake or excretion and BMD. Conclusions: in this cross-sectional study we could not confirm significant correlation between BMD and sodium intake or excretion. We also could not relate osteoporosis to the amount of calcium ingested. However, based on urine analyses, we con.rmed significant relationship between calcium and sodium metabolism. Longitudinal analysis is probably necessary to get better insight of calcium and sodium influence on bone.
bone mass; sodium; calcium
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Podaci o prilogu
S103-x.
2006.
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objavljeno
Podaci o matičnoj publikaciji
Calcified tissue international
Springer Science+Business Media
0171-967X
Podaci o skupu
33rd European Symposium on Calcified Tissues
poster
10.05.2006-14.05.2006
Prag, Češka Republika
Povezanost rada
Javno zdravstvo i zdravstvena zaštita