Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Cu(II) complexes of nitrogen ligand - oligopeptide conjugates as potential artificial nucleases (CROSBI ID 540542)

Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija

Kirin, Srećko I. ; Happel, Christoph M. ; Klein, Christoph ; Metzler-Nolte, Nils Cu(II) complexes of nitrogen ligand - oligopeptide conjugates as potential artificial nucleases // Proceedings of SPS-8, The eight international symposium: Innovation and perspectives in solid phase synthesis and combinatorial libraries / Epton, Rodger (ur.). Kingston: Mayflower Worldwide Ltd., 2004. str. 261-262

Podaci o odgovornosti

Kirin, Srećko I. ; Happel, Christoph M. ; Klein, Christoph ; Metzler-Nolte, Nils

engleski

Cu(II) complexes of nitrogen ligand - oligopeptide conjugates as potential artificial nucleases

In this work, the nitrogen ligand bpa (bispicolylamine) was conjugated to the oligopeptide nls (nuclear localization signal, PKKKRKV) by solid phase peptide synthesis, yielding bioconjugate 2. The binding of 2 and Cu(II) was studied by UV/VIS and MS and compared with the isolated well-defined simple bpa complex 1Cu. The results indicate similar structural features of 1Cu and the in situ prepared metal bioconjugate 2Cu. At present our efforts are focused on the evaluation of nuclease activity of bioconjugate 2Cu.

artificial enzymes; copper(II) complexes; peptides; solid phase peptide synthesis

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

261-262.

2004.

objavljeno

Podaci o matičnoj publikaciji

Proceedings of SPS-8, The eight international symposium: Innovation and perspectives in solid phase synthesis and combinatorial libraries

Epton, Rodger

Kingston: Mayflower Worldwide Ltd.

Podaci o skupu

Nepoznat skup

poster

29.02.1904-29.02.2096

Povezanost rada

Povezane osobe




Kemija, Biologija