Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi

Compositional analysis, cytotoxic and cytoprotective activity of red raspberry leaves extract (CROSBI ID 576385)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Durgo, Ksenija ; Stančić, Angela ; Belščak-Cvitanović, Ana ; Komes, Draženka ; Curcic, Marijana ; Antonijević, Biljana ; Dinter, Domagoj ; Franekić, Jasna Compositional analysis, cytotoxic and cytoprotective activity of red raspberry leaves extract // FIP 2011 abstracts. 2011

Podaci o odgovornosti

Durgo, Ksenija ; Stančić, Angela ; Belščak-Cvitanović, Ana ; Komes, Draženka ; Curcic, Marijana ; Antonijević, Biljana ; Dinter, Domagoj ; Franekić, Jasna

engleski

Compositional analysis, cytotoxic and cytoprotective activity of red raspberry leaves extract

The polyphenolic profile and antioxidant properties of red raspberry (Rubus idaeus L.) leaf extract were determined and examined for potential biological activity. The content of phenolic compounds and the antioxidant capacity of red raspberry leaf extract were determined using UV/Vis spectrophotometric methods and high-performance liquid chromatography. Red raspberry leaf extract exhibited a significant content of total phenols (40.64 mg GAE/g dw), with quercetin derivatives constituting the most abundant polyphenolic compounds, followed by ellagic acid derivatives, while caffeic and chlorogenic acids were also represented in a high content. Cytotoxic, antioxidative/prooxidative effect and total glutathione (GSH) concentration of red raspberry leaf extract were determined on human laryngeal carcinoma cell line (Hep-2) and adenocarcinoma of the colon (SW 480). SW 480 cells are more susceptible to raspberry leaf extract in comparison to Hep-2 cells. Antioxidative nature of raspberry leaf extract was detected in the Hep-2 cells treated with hydrogen peroxide, as opposed to SW 480 cells where raspberry leaf extract induced reactive oxygen species formation. Raspberry leaf extracts increased GSH level in Hep-2 cells. GSH level increased in the cells that were previously treated with hydrogen peroxide and this effect was reinforced after 24 hours of recovery. In SW 480 cells, lower concentrations of extract increased, while higher concentrations decreased total GSH level with no influence on cells treated with hydrogen peroxide.

Antioxidant activity ; Cytotoxicity ; Glutathione ; Polyphenols ; Red raspberry leaves

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

6107

2011.

nije evidentirano

objavljeno

Podaci o matičnoj publikaciji

FIP 2011 abstracts

Podaci o skupu

71st congress of the International Pharmaceutical Federation (FIP)

poster

03.09.2011-08.09.2011

Hyderābād, Indija

Povezanost rada

Prehrambena tehnologija

Poveznice