Mitochondrial DNA variability in Macedonians and Macedonian Romani: implication to the role in human forensic identification (CROSBI ID 598502)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Havaš Auguštin, Dubravka ; Novokmet, Natalija ; Šarac, Jelena ; Šarić, Tena ; Cvjetan, Svjetlana ; Efremovska, Ljudmila ; Đorđević, Dobrivoje ; Missoni, Saša ; Villems, Richard ; Rudan, Pavao
engleski
Mitochondrial DNA variability in Macedonians and Macedonian Romani: implication to the role in human forensic identification
In this study we have analyzed a mitochondrial DNA diversity in a sample of 140 unrelated autochthonous Macedonians and 159 Macedonian Romany, representing different ethnical groups residing within the same country of Republic of Macedonia. Based on high resolution analysis of both coding and non-coding regions of mitochondrial genomes, to each of the sample haplogroup and subhaplogroup affiliation was determined. Population of Macedonians represent quite typical European population, with highest frequency of haplogroup H (42.85%), followed by hg U (17.86%), T (11.43%), J (7.85%) and K(3.57%). The other, less frequent haplogoups, also take part in shaping the maternal genetic pool of this population. On the other hand Macedonian Romani, as an example of endogamous population of Indian origin, shows significant departure from haplogruop composition and frequencies when compared to Macedonians. The highest frequency represent M5a1 haplogroup (38.36%), untypical for any European population, but very common among Indian and Romany populations. Second most frequent haplogroup is hg H (22.64%), but only two haplotypes of hg H20 and H7a1 encompass one half of this haplogroup’s diversity. Hg X2 (mostly represented by X2e1), present with less than 1% in typical European population makes more than 10% of maternal gene pool of Macedonian Romany population. This data could have their potential role in human identification as an additional tool in forensic science community.
mitochondrial DNA; Macedonians; Macedonian Romani; haplogroup diversity; forensic identification
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Podaci o prilogu
215-215.
2013.
objavljeno
Podaci o matičnoj publikaciji
PROGRAM AND ABSTRACTS The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine
Vuk-Pavlović, Stanimir ; Primorac, Dragan ; Schanfield, Moses
Zagreb: International Society for Applied Biological Sciences (ISABS)
978-953-57695-0-7
Podaci o skupu
The Eighth ISABS Conference in Forensic, Anthropologic and Medical Genetics and Mayo Clinic Lectures in Translational Medicine
poster
24.06.2013-28.06.2013
Split, Hrvatska