The link between NP-C and Alzheimer’s disease (CROSBI ID 605078)
Neobjavljeno sudjelovanje sa skupa | neobjavljeni prilog sa skupa | međunarodna recenzija
Podaci o odgovornosti
Katušić Hećimović, Silva
engleski
The link between NP-C and Alzheimer’s disease
We found that an Alzheiemr's disease-like phenotype in Niemann-Pick type C disease is due to APP and BACE1 accumulation within endocytic compartments leading to increased APP processing by beta-secretase and increased amyloid-beta formation.
Alzheimer's disease; amyloid-beta; APP; NPC1; lysosomal storage diseases
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Podaci o prilogu
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Podaci o skupu
Pharmaceuticals Ltd. Joint International Advisory Board Meeting on Niemann-Pick Type C
pozvano predavanje
10.05.2012-10.05.2012
Zürich, Švicarska
