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Molecular mechanism(s) of increased Aß upon cholesterol accumulation in Niemann-Pick type C disease (CROSBI ID 605082)
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Katušić Hećimović, Silva
Molecular mechanism(s) of increased Aß upon cholesterol accumulation in Niemann-Pick type C disease // German Center for Neurodegenerative Diseases Munich - Seminar
München, Njemačka, 10.06.2011-10.06.2011
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Katušić Hećimović, Silva
engleski
Molecular mechanism(s) of increased Aß upon cholesterol accumulation in Niemann-Pick type C disease
We demonstrated that enhanced cholesterol levels in NPC1-null cells lead to increased processing of APP by beta-secretase and increased amyloid-beta production.
Alzheimer's disease; cholesterol; amyloid-beta; NPC1
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German Center for Neurodegenerative Diseases Munich - Seminar
pozvano predavanje
10.06.2011-10.06.2011
München, Njemačka
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