engleski

Sex-related differences in genetic susceptibility to toxic metals.

Protection of human health by prevention of environmental hazards had been a major concern in all European countries since the regional strategy of 'Health for All by the Year 2000', as developed in 1984, and in the 1989 'European Charter on Environment and Health'. The chapter under above title in this edition contains data on gender-related differences in susceptibility to selected toxic metal effects, as documented by examples of own results obtained in experiments on laboratory rats (Wistar). However, to that point, animal models have been of little help in elucidating the genetic basis of toxic reactions in humans due to species differences. It was recognized later (by a book presenter in 1992) that strain differences would better point to genetic factors in experimental animal model systems.

gender difference, toxic metals, laboratory rats

Chapter in an international edition on invitation.