Development and validation of LC-MS/MS method for quantification of opiorphin in human saliva (CROSBI ID 616266)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Brkljačić Lidija ; Sabalić, Maja ; Salarić, Ivan ; Jerić, Ivanka ; Alajbeg, Ivan ; Nemet, Ina
engleski
Development and validation of LC-MS/MS method for quantification of opiorphin in human saliva
Using opiorphin as a potential biomarker of different pathological states requires the development of robust and sensitive methods. We developed a highly sensitive and specific liquid chromatography with tandem mass spectrometric detection (LC–ESI–MS/MS) analytical method for the analysis of opiorphin in human saliva with limited sample manipulation. The analytical method for determination of opiorphin in the human saliva was also validated on the following parameters: linearity, limit of detection (LOD), lower limit of quantification (LLOQ), precision, accuracy, recovery, matrix effect and sample stability.
Opiorphin ; LC-ESI-MS/MS ; Saliva
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Podaci o prilogu
48-48.
2012.
objavljeno
Podaci o matičnoj publikaciji
Book of abstracts of the 13th International Chromatography School
Podaci o skupu
13th International Chromatography School
poster
18.06.2012-19.06.2012
Zagreb, Hrvatska