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Physical and Histologic Properties of Substitutes Used for the Anterior Fossa Region Dural Repair (CROSBI ID 211773)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Vranković, Đuro ; Mrčela, Tomislav ; Muršić, Božidar ; Splavski, Bruno ; Dmitrović, Branko ; Mrčela, Milanka ; Blagus, Goran Physical and Histologic Properties of Substitutes Used for the Anterior Fossa Region Dural Repair // Skull base surgery, 9 (1999), 1; 9-13

Podaci o odgovornosti

Vranković, Đuro ; Mrčela, Tomislav ; Muršić, Božidar ; Splavski, Bruno ; Dmitrović, Branko ; Mrčela, Milanka ; Blagus, Goran

engleski

Physical and Histologic Properties of Substitutes Used for the Anterior Fossa Region Dural Repair

During the last 10 years, 41 patients with dural tear caused by anterior cranial fossa bone fracture were treated surgically. Those treated conservatively were not included in this series. The patients' mean age was 36 years. The average time of postoperative observation was 15 months. Traffic accidents, as well as wounds caused by missiles (shell fragments or bullets), blows, and fall were the mechanisms of injury. An autogenous graft, followed by homologous (lyodura) and most recently by heterologous (lyoplant ; B. Braun Melsungen AG, Melsungen, Germany) implants, was used to repair the dural lacerations. Fibrin adhesive was used to seal the sutures inserted between graft and dural defect margins in a majority of cases. The following criteria are required for the best dural substitute: uncontaminated tissue, histologic similarity to the local dura mater, adaptability, quick rehidratation, waterproof closure and the dural margins fast healing, and tensile strength easily resisting cerebrospinal fluid pressurization in physiological and pathological conditions. To define the effects of different tissue that could meet the above- mentioned criteria, we have undertaken a mechanical testing of the dural substitutes' tensile strength followed by histologic examination, and comparison with the dura mater of the anterior fossa region. Finally, we have paid particular attention to the clinical results of these substitutes.

dural repair; dural substitutes

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Podaci o izdanju

9 (1)

1999.

9-13

objavljeno

1052-1453

Povezanost rada

Kliničke medicinske znanosti

Indeksiranost