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izvor podataka: crosbi

Do the circulating respiratory syncytial virus genotypes effect biennial epidemic periodicity in Croatia? (CROSBI ID 631014)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa

Mlinarić-Galinović, Gordana ; Forčić, Dubravko ; Ivančić-Jelečki, Jelena ; Vojnović, Gordana ; Božikov, Jadranka ; Welliver, Robert C. Do the circulating respiratory syncytial virus genotypes effect biennial epidemic periodicity in Croatia? // International journal of medical microbiology (Print). 2012. str. 86-86 doi: 10.1016/j.ijmm.2012.08.001

Podaci o odgovornosti

Mlinarić-Galinović, Gordana ; Forčić, Dubravko ; Ivančić-Jelečki, Jelena ; Vojnović, Gordana ; Božikov, Jadranka ; Welliver, Robert C.

engleski

Do the circulating respiratory syncytial virus genotypes effect biennial epidemic periodicity in Croatia?

The biennial epidemic pattern of respiratory syncytial virus (RSV) circulation in Croatia has been preserved and could not be related to climatic factors and the predominant RSV subtypes. The possibility that the circulation of different RSV genotypes affect the outbreak cycle in children in Croatia (Zagreb region) over a period of 3 consecutive years was explored in the paper. Methods: The study group consisted of inpatients, aged 0 - 10 years, who were hospi- talized with acute respiratory tract infections caused by RSV, in Zagreb, over the period from 1 January 2006 to 31 De- cember 2008. The virus was identified in the nasopharyngeal secretion using direct immunofluorescence method. The virus subtype and genotype was determined by real-time PCR and sequence analysis, respectively. Results: RSV infec- tions identified in 731 children. RSV subtype A caused 399 infections, and subtype B 332. Two subtype A genotypes (NA1 and GA5) and three subtype B genotypes (BA7, BA9 and BA10) were found. During persistent RSV biennial cycles namely four succeeding outbreaks, the new genotype from the previous smaller outbreak persevered into the up- coming larger outbreak. Conclusion: Our molecular-epidemiology study of RSV subtypes and genotypes during calen- dar months demonstrates that the biennial RSV cycle cannot be fully explained by the dynamic of the predominant cir- culating genotype of RSV. Other unknown factors account for the biennial cycle of RSV epidemics in Croatia.

spiratory syncytial virus ; genotypes ; epidemic periodicity

u CC-u pod skupnim naslovom: 64th Annual Meeting of the German Society for Hygiene and Microbiology (DGHM) Abstracts, Hamburg, Germany, September 30 to October 3 2012 Abstracts

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Podaci o prilogu

86-86.

2012.

nije evidentirano

objavljeno

10.1016/j.ijmm.2012.08.001

Podaci o matičnoj publikaciji

International journal of medical microbiology (Print)

1438-4221

Podaci o skupu

Jahrestagung der Deutschen Gesellschaft fur Hygiene und Mikrobiologie (64 ; 2012)

poster

30.09.2012-03.10.2012

Hamburg, Njemačka

Povezanost rada

Biologija, Javno zdravstvo i zdravstvena zaštita

Poveznice