engleski

Preparation of antibacterial electrospun scaffold for skin cells culture

In this work the function and application of titanium dioxide as a filler in a composite system polycaprolactone/titanium dioxide (PCL/TiO2) was examined. Titanium dioxide was applied by ultrasonic bath on already electrospun PCL fibrous scaffold treated and non-treated with NaOH. A procedure of surface modification of the electrospun PCL fibrous scaffold was made to enhance the interaction of the surface with the TiO2 particles. The surface modification was performed using NaOH for the formation of carboxyl groups on the fibers‘ surfaces. The water contact angle was measured by goniometer to prove the change from hydrophobic to hydrophilic polymer surface. SEM was used to study the morphology structure of the electrospun PCL fibrous scaffold before and after NaOH treatment and introduction of TiO2. The content of TiO2 on the electrospun PCL fibrous scaffold was determined by TGA.

Electrospinning, NaOH, surface modification, titanium dioxide

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