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Novel diastereomeric thymidine cyclic 3', 5'-threo-phosporamidates (CROSBI ID 80974)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Katalenić, Darinka ; Žinić, Mladen Novel diastereomeric thymidine cyclic 3', 5'-threo-phosporamidates // Nucleosides & nucleotides, 17 (1998), 7; 1231-1236. doi: 10.1080/07328319808004235

Podaci o odgovornosti

Katalenić, Darinka ; Žinić, Mladen

engleski

Novel diastereomeric thymidine cyclic 3', 5'-threo-phosporamidates

Novel diastereomeric thymidine cyclic 3', 5'-threo-phosphoramidates were prepared by the treatment of 5'-azido derivative of threo-thymidine with triphenyl phosphite as well as by the treatment of the corresponding amino derivative with phenyl phosphodichloridate. Phosphoramidation of the regioisomeric 3'- and 5'-azido derivatives of erythro-thymidine by means of triphenyl phosphite afforded the open-chain 3'- and 5'-phosphoramidates. The reaction which afforded the cyclic products was assumed to proceed via the cyclic tetraoxazaphosphorane intermediates.

nucleosides ; thymidine ; phosphoramidates

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Podaci o izdanju

17 (7)

1998.

1231-1236

objavljeno

0732-8311

10.1080/07328319808004235

Povezanost rada

Kemija

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