(2R, 3R) 3-Amino-1-(1`-methyloxycarbonyl-2-methyl-prop-1`-enyl)-4-oxoazetidine-2-sulphonic Acid Monohydrate: New Chiral beta-lactam Synthon (CROSBI ID 77435)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Mandić, Zorica ; Kiralj, Rudolf ; Kojić-Prodić, Biserka ; Kovačević, Miće
engleski
(2R, 3R) 3-Amino-1-(1`-methyloxycarbonyl-2-methyl-prop-1`-enyl)-4-oxoazetidine-2-sulphonic Acid Monohydrate: New Chiral beta-lactam Synthon
The title compound, a novel monocyclic [beta]-lactam, was prepared and chemically characterized by IR and 1H NMR spectroscopy and X-ray structure analysis. C9H14N2O6S.H2O exists as a zwitterion crystallized with a water molecule. The four-membered lactam ring is slightly puckered, the ammonio and sulfonate groups are cis, and the aliphatic substituent is trans to these polar groups. Hydrogen bonds link the zwitterions and the water molecules into spirals parallel to the b axis, forming a two-dimensional network with base vectors along (100) and (010).
synthesis; X-ray structure analysis; beta-lactams
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o izdanju
52 (4)
1996.
988-991
objavljeno
0108-2701