7-Cyclopentyl-5-(4-phenoxypheny)-7H-pyrrolo(2, 3-d)pyrimidine-4-yl-amine, an lck tyrosine kinase inhibitor (CROSBI ID 113506)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Banić Tomišić, Zrinka ; Čempuh, Andreja ; Malnar, Ivica
engleski
7-Cyclopentyl-5-(4-phenoxypheny)-7H-pyrrolo(2, 3-d)pyrimidine-4-yl-amine, an lck tyrosine kinase inhibitor
The molecular and crystal structures of the potent and selective tyrosine kinase inhibitor, C23H22N4O, have been determined by single-crystal X-ray diffraction. The pyrrolopyrimidine and phenyl rings are planar while the cyclopentyl ring adopts a conformation between envelope and half-chair. The overall conformation is defined by the spatial arrangement of the ring moieties.
molecular and crystal structure ; lck tyrosine kinase inhibitor
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Podaci o izdanju
E57
2001.
o511-o513
objavljeno
1600-5368