Synthesis and reactivity of the monosaccharide esters of amino acids as models of teichoic acid fragment (CROSBI ID 86664)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Jerić, Ivanka ; Šimičić, Lidija ; Stipetić, Marina ; Horvat, Štefica
engleski
Synthesis and reactivity of the monosaccharide esters of amino acids as models of teichoic acid fragment
Due to the enhanced reactivity of the NH2 group in the monosaccharide esters studied, the formation of products generated by intramolecular and intermolecular glycation reactions is accelerated resulting in heterogeneous mixture of products. These findings suggest that similar adducts formed by glycation of D-alanine in teichoic acid of Gram-positive bacteria, should be examined as potential bioactive ligands or chemical message for infection.
monosaccharide; amino acid; ester; glycation; teichoic acid; Gram-positive bacteria
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