engleski

New amidino-substituted benzimidazolyl furyl-thienyl acrylates and benzothienofurans: Synthesis and photochemical synthesis

New amidino-substituted benzimidazolyl 3-(2-furyl)-2-(2-thienyl)acrylates 4-6, benzo[1, 2-b]thieno-benzo[4, 3-b’]furans 8-10 were prepared by the condensation of amidino-substituted o-phenylenediamines with corresponding aldehydes 3 and 7. All prepared amidino-substituted compounds could serve as intercalators or groove binders of DNA in HIV infection.

substituted benzimidazolyl 3-(2-furyl)-2-(2-thienyl)acrylates; benzo[1; 2-b]thieno-benzo[4; 3-b’]furans; anti-HIV agents; groove-binders

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