engleski

Interactions of phenanthridinium-nucleobase conjugates with polynucleotides in aqueous media. Recognition of poly U

Adenine containing conjugates 4 and 5 exhibit specific spectroscopic changes and two orders of magnitude higher affinity toward poly U than uracil conjugates 2 and 3 and the reference compound 1 due to the existence of specific interactions between adenine and uracil, possibly Watson-Crick hydrogen bonding between the bases stacked on the phenanthridinium moiety.

phenanthridinium-nucleobase conjugates ; recognition ; poly U

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