engleski

Preparation and evaluation of brush-type chiral stationary phases for liquid chromatography

The new CSPs are proved effective for the resolution of several classes of compounds and particularly for 4-aryl-3, 4-dihydro-2-(1-H)-pyrimidone derivates (DHPM’ s). These heterocycle compounds exhibit various important pharmacological properties, e.g. acting as antihypertensive agents, α -1a-adrenergic antagonists, or neuropeptide Y antagonists.

HPLC; enantiomer; chiral stationary phases

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