Decreased Complexity of Serum N-glycan Structures Associates with Successful Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection (CROSBI ID 284426)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Monaghan, Tanya M. ; Pučić-Baković, Maja ; Vučković, Frano ; Lee, Christine ; Kao, Dina ; Wójcik, Iwona ; Kliček, Filip ; Polytarchou, Christos ; Roach, Brandi ; Louie, Tom ; Kim, Peter ; Roach, Brandi ; Polytarchou, Christos ; Frankowski, Marcin ; Lauc, Gordan
engleski
Decreased Complexity of Serum N-glycan Structures Associates with Successful Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection
N-glycosylation is a common and yet complex posttranslational process that covalently links glycans (complex oligosaccharides) to proteins and lipids, affecting cellular structure and function. Glycans have important biological functions in protein maturation and turnover, cell adhesion and trafficking, and receptor binding and activation. 1 In the immune system, glycosylation also modulates the function of immunoglobulin G (IgG).
FMT ; glycans
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Podaci o izdanju
157 (6)
2019.
1676-1678
objavljeno
0016-5085
1528-0012
10.1053/j.gastro.2019.08.034