Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi

Galectin-3: An open-ended story (CROSBI ID 122163)

Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija

Dumić, Jerka ; Dabelić, Sanja ; Flogel, Mirna Galectin-3: An open-ended story // Biochimica et biophysica acta. G, General subjects, online (2006), online-x

Podaci o odgovornosti

Dumić, Jerka ; Dabelić, Sanja ; Flogel, Mirna

engleski

Galectin-3: An open-ended story

Galectins, an ancient lectin family, are characterized by specific binding of beta-galactosides through evolutionary conserved sequence elements of carbohydrate-recognition domain (CRD). A structurally unique member of the family is galectin-3 ; in addition to the CRD it contains a proline- and glycine-rich N-terminal domain (ND) through which is able to form oligomers. Galectin-3 is widely spread among different types of cells and tissues, found intracellularly in nucleus and cytoplasm or secreted via non-classical pathway outside of cell, thus being found on the cell surface or in the extracellular space. Through specific interactions with a variety of intra- and extracellular proteins galectin-3 affects numerous biological processes and seems to be involved in different physiological and pathophysiological conditions, such as development, immune reactions, and neoplastic transformation and metastasis. The review attempts to summarize the existing information on structural, biochemical and intriguing functional properties of galectin-3.

Galectin-3; LGALS3; Structure; Expression; Tissue distribution; Functional properties; Immune reaction; Cancer

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o izdanju

online

2006.

online-x

objavljeno

0304-4165

Povezanost rada

Biologija

Poveznice
Indeksiranost