Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Physical characterization of "Split" vaccine against infectious bronchitis in chickens prepared as water-in-oil-in-water emulsion (CROSBI ID 537339)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Herak-Perković, Vlasta ; Pavelić, Željka ; Tišljar, Marina ; Savić, Vladimir ; Ergotić, Neda ; Čajevac, Stanislav Physical characterization of "Split" vaccine against infectious bronchitis in chickens prepared as water-in-oil-in-water emulsion // Proceedings of 2nd Croatian Congress of Microscopy with International Participation. 2006. str. 222-x

Podaci o odgovornosti

Herak-Perković, Vlasta ; Pavelić, Željka ; Tišljar, Marina ; Savić, Vladimir ; Ergotić, Neda ; Čajevac, Stanislav

engleski

Physical characterization of "Split" vaccine against infectious bronchitis in chickens prepared as water-in-oil-in-water emulsion

"Split" vaccine against infectious bonchitis, prepared in Veterina Ltd., contained the IB virus propagated in embrionated hen eggs from specified pathogen-free (SPF) flocks. The virus is inactivated with 0.04% formaldehyde, and entrapped in the vaccine that was prepared in form of water-in-oil-in-water emulsion (WOWE). WOWE were tested for physical stability (as regards droplet size and distribution) after 3 and 6 month of storage at room temperature what is the stress condition for vaccines. The technology of image analysis of microscopical picture by application of the two systems for particle characterization was employed ; a digital microscopy camera system Axioscop with computer software for visualization and interactive morphometry, and Olympus BH-2 with Optomax V equipment for automatic measurements. After 6 months storage at stress condition (20°C), the mean diameter of WOWE droplets changed from 1.0653 to 1.2143 micrometers, but the distribution remained statistically similar. During the observed period the values of mean droplet diameter slightly increased from 100 to 200 nm. The results obtained by image analysis microscopy techniques demonstrated that tested WOWE remained very stable after 6 months storage under unsuitable conditions.

vaccine; virus; microscopy; emulsion; stability

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

222-x.

2006.

objavljeno

Podaci o matičnoj publikaciji

Proceedings of 2nd Croatian Congress of Microscopy with International Participation

Podaci o skupu

2nd Croatian Congress of Microscopy with International Participation

poster

18.05.2006-21.05.2006

Topusko, Hrvatska

Povezanost rada

Farmacija