engleski

High Throughput Plasma N-Glycome Profiling using Multiplexed Labelling and UPLC with Fluorescence Detection

A rapid glycomic profiling method is described wherein N-glycans from plasma samples individually labelled with aniline, 2-aminobenzamide and 2- aminoacridone are mixed, co-injected and separated in the same HILIC-fluorescence run. Transfer of the multiplexed method to UPLC-fluorescence permits an increase in sample throughput from 24 to 864 plasma samples per day.

aniline ; 2-aminobenzamide ; 2-aminoacridone ; glycan analyses

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