engleski

Influence of anticoagulants on detected level of Zn in plasma

The aim of this study was to check the influence of anticoagulants on detected level of Zn in plasma and compare it with detected level of Zn in serum. For that purpose blood samples from the same blood donor (n = 10) were sampled on various anticoagulants and to obtain serum, no anticoagulant was used. In plasma or serum samples Zn level was determined by flame atomic-absorption spectrometer. The level of Zn in plasma collected on different anticoagulants and in serum was in reference range (0.7 to 1.5 μg/ml) and did not differ indicating that anticoagulants do not have impact on detected level of Zn in plasma or serum. However, correlation was observed only between Zn level in plasma samples collected by use of citrate and heparin (rs = 0.723) and citrate and Zn level in serum (rs = 0.764). Although our results indicate that anticoagulant do not have effect on the detected level of Zn in plasma/serum sample, nevertheless the impact of anticoagulant cannot be overlooked when comparing results of Zn level in plasma from various studies

zinc, plasma, serum, anticoagulants

nije evidentirano