engleski

Viability of human glioblastoma cell line LN229 exposed to rotating magnetic field

This study focuses on in-vitro research regarding rotating magnetic field (RMF) exposure as a new treatment possibility for glioblastoma multiforme (GBM) - highly destructive malignant brain tumor in humans. In this study we demonstrated that exposure of LN229 GBM cells to 0.4T 10 Hz RMF resulted in ambiguous data regarding cell viability. Some exposure protocols (12h/day for 2 days) resulted in statistically significant reduction of tumor cell viability after exposure to aforementioned RMF while others (3h/day for 3 days) resulted in increased cell viability. Larger, comparative study using multiple cell lines, different exposure parameters and protocols, should be performed before a final conclusion about the link between viability of human glioblastoma cells and rotating magnetic field exposure can be made.

glioblastoma multiforme ; rotating magnetic field ; cell viability ; in-vitro research

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