engleski

Capabilities of "Thanatos" computer system in creating of specific register for thyroid diseases

"Thanatos" computer system for clinical pathology memorises and processes diagnoses coded according to the International Classification of Diseases and Related Health Problems (tenth revision, 1994). We have used mentioned system to build up a specific register for thyroid diseases, and "Thanatos" was expected to fulfil several demands: a) to memorise diagnoses obtained from surgery, b) to differentiate malignant from benign lesions, and c) to differentiate stages of diseases. Between 1992 and 1996, 806 patients were submitted to surgery for partial or total thyroidectomy. Out of total, 722 lesions were benign (89, 6%), and 84 lesions were malignant (10, 4%), giving a proportion of 8, 6:1. Benign findings were established as follows: follicular adenoma in 245 cases, nodular goitre 360, diffivse goitre 31, Hashimoto's disease 32, Graves' disease 6, and diffuse hyperplasia 48 cases. Malignancies were classified as follows: well-differentiated carcinoma 71 (papillary, 64 cases and follicular, 7 cases), medullary carcinoma 10, and anaplastic carcinoma 3 cases. We have also challenged "Thanatos" system with more complicated task - correlation of the primary tumour size with metastatic rate to local lymph nodes. Model was the most common type - papillary carcinoma. Among metastases free patients primary tumour measured 16, 3&plusmn ; ; 12 mm. Lymphatic spread had 31, 2% of patients, with tumour diameter of 17, 5&plusmn ; ; 11 mm. Difference between the two was not statistically significant, leading to conclusion that size of primary tumour does not predict malignant potential of the papillary thyroid carcinoma. In presented work we have demonstrated, on the example of register for thyroid diseases, that "Thanatos" computer system for clinical pathology is reliable in memorising of pathological data and very useful in their analysis, providing valuable scientific data on prevalence and nature of various pathological conditions.

computer medical systems; thyroid carcinoma; register for thyroid diseases

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