engleski

OROFACIAL SYMPTOMS IN PATIENTS WITH MULTIPLE SCLEROSIS.

Aim: Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system affecting the sensory and motor nervous conduction. The disease may also have manifestations in the orofacial region. The aim of this study was to determine the prevalence of orofacial symptoms in the group of patients with multiple sclerosis and to investigate the correlation of the symptoms with the disease parameters. Materials and Methods: The study included 33 patients with MS (24 women and 9 males, mean age 56.30 +/- 9.16) and 33 healthy subjects who did not suffer from MS (24 women and 9 males, mean age 57.56 +/- 9.02). Participants filled out a questionnaire about the occurrence of orofacial symptoms, and the patients with MS were also asked about the duration and type of disease. Results: MS patients have more orofacial symptoms than the control subjects. The most frequent orofacial symptoms in the MS patients compared to the control subjects were: dry mouth (54.5% vs. 27.5% ; p=0.86), swallowing problems (42.4% vs. 3.3% ; p<0.001), impaired speech (42.4% vs. 0% ; p=0.0001), taste change (36.3% vs. 3.3% ; p<0.001), cramps in the face and mouth (27.2% vs. 0% ; p=0.004), pain in the mouth (21.2% vs. 3.3% ; p=0.02), temporomandibular joint pain (21.2% vs. 0% ; p=0.01) face pain (18.1% vs. 0% ; p=0.03) and burning in the mouth (12.1% vs. 3.3% ; p=0.162). There was no statistically significant correlation between the number of orofacial symptoms and MS duration.

orofacial symptoms ; multiple sclerosis

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