engleski

White wine consumption and rats weight: Do polyphenols matter?

Introduction: Moderate wine consumption isn’t associated with weight gain although wine is a rich source of energy. Among proposed explanations for this is possible role of wine phenolics on food intake, gastrointestinal energy harvest and/or nutrients metabolism. In order to evaluate this assumption, we compared effects of 4 weeks consumption of standard and polyphenols-rich white wine (PRWW) on weight gain in rats. Materials and methods: Sprague Dawley male rats, weighing 150-200 g were assigned into 3 groups, standard white wine, PRWW and water-only-drinking controls (N=10 per group). The wine drinking rats were offered standard or PRWW (total phenolic content 210 and 2699 mg GAE/L, respectively) ad libitum 24 hours/day with daily inclusion of tap water for 6 hours. PRWW was obtained by Georgian traditional wine-making in which white grape juice is fermented and left in long contact with the hard parts of grape. Fluids intake was recorded daily. Body weight and food intake were measured weekly. Results: After 4 weeks both standard and PRWW-drinking rats gained less weight in comparison to controls (171, 164, and 200 g, respectively). Further, total food intake was reduced in the wine-drinking rats, but to the greater extent in animals drinking PRWW (574 g-PRWW, 657 g-standard white wine and 729 g-controls). Rats that drank PRWW showed tendency to lesser weight gain relative to the standard white-wine-drinking animals. Conclusion: Consumption of standard and PRWW is associated with decreased food intake and weight gain in rats. Wine phenolics have additional effect on reduction of food intake.

Wine Phenolics ; White Wine ; Weight Gain

nije evidentirano