engleski

Modelling of reaction kinetics for reactor selection in the case of L-erythrulose synthesis

To choose the most effective process design in enzyme process development it is important to find the most effective reactor mode of operation. This goal is achieved by modeling of the reaction kinetics as a tool of enzyme reaction engineering. With the example of the transketolase catalyzed L-erythrulose synthesis we demonstrate how the most effective reactor mode can be determined by kinetic simulation. This is of major importance if the biocatalyst deactivation is caused by one of the substrate as in this case by glycolaldehyde. The cascade of two membrane reactors in series with soluble enzyme is proposed as a solution for enzyme deactivation by one of the substrate.

Enzymatic synthesis of L-erythrulose; Transketolase; Modeling of enzyme kinetics; Selection of enzyme reactor

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