engleski

Sero-survey of Q fever in the north-western part of Bosnia and Herzegovina

Aim: To assess the prevalence of antibodies to Coxiella burnetii phase II antigen in sera of people living in the north-western part of Bosnia and Herzegovina (Bihać area). Methods: One hundred eighty-three human sera were tested by complement fixation (CF), indirect immunofluorescence (IFA), and indirect enzyme immunoassay (EIA) for antibodies against Coxiella burnetii phase II antigen. Results: Twenty-four percent of CF- tested sera reacted positively to phase II antigen of Coxiella burnetii. In the IFA and EIA tests, 22.4% of sera reacted with C. burnetii. IFA and EIA test results agreed in all cases. Conclusion: The results of the serosurvey show that Coxiella burnetii is endemic in the north-western part of Bosnia and Herzegovina. In a seroepidemiological survey of Q fever, indirect enzyme immunoassay is equivalent to indirect immunofluorescence assay.

Bosnia and Herzegovina; complement fixation test; Coxiella; enzyme immunoassay; immunofluorescence technic

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