engleski

BIHEMISPHERICAL CEREBRAL GANGLIOGLIOMA AND HEMANGIOMATOUS MALFORMATION IN AN 18-MONTH-OLD-CHILD ; CASE REPORT

In this paper a rare case of concomitant bihemispherical cerebral ganglioglioma and hemangiomatous malformation in an 18-month-old boy is presented. Gangliogliomas are relatively uncommon tumours in childhood. They consist of a mixture of glial cells and differentiated nerve cells, and represent true neoplasms with the potential for progressive growth. The child underwent diagnostic neuroimaging examinations (CT and MRI) for seizures and right-sided facial palsy that showed the bilaterally presence of parieto-occipital, oval, well demarcated, subcortically processes. A biparieto-occipital craniotomy was carried out and two well-demarcated abnormalities were detected and removed in toto. Three years after the operation, the boy experienced normal psychomotor development and remained free from seizures with no therapy required. Repeat MRI showed no tumour recurrence. Histopathologic and immunohistochemical analysis of the two processes found in our patient showed them to be a ganglioglioma and a hemangiomatous malformation, confirming the dysontogenetic origin of these alterations and association between malformations and tumour growth. The combination of ganglioglioma and hemangiomatous malformation, especially bilateral presentation of such two identical processes in a young child is very rare and was not found in the recent literature.

bihemispherical cerebral ganglioglioma

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