Antiandrogens in hormonal contraception limit muscle strength gain in strength training: Comparison study (CROSBI ID 102949)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Ružić, Lana ; Matković, Branka ; Leko, Goran
engleski
Antiandrogens in hormonal contraception limit muscle strength gain in strength training: Comparison study
Aim. To determine antiandrogen effects on muscle strength gain and fat-free mass increase during exercise in women using hormonal contraception with antiandrogen content. Methods. The study included 50 women (age range, 18-30 years ; mean +/- SD, 26 +/- 3) using hormonal contraception for at least 12 months before the beginning of the study. They were divided into two groups: "anti androgen" group (n = 26) and "estrogen-progestogen" group (n = 24) groups. The subjects participated in strength training sessions 3 times a week during 16 weeks. Initially, there were no differences between the groups in fat-free mass, muscle strength, or maximum oxygen uptake. The parameters were measured before, during, and after the training period. Results. After the training period, the mean increase of fat-free mass was significantly greater in the estrogen-progestogen group (p < 0.001). The mean gain in the muscle strength (in Newtons) was also more evident in estrogen-progestogen group (1289.0 +/- 17.1 N vs 101.9 +/- 18.5 N ; p < 0.001). There were no differences in the maximum oxygen consumption (VO(2)max). Conclusion. Antiandrogens had a negative effect on muscle strength, minimizing the effects of strength training in women. Hormonal contraception containing antiandrogens should be avoided in young exercising women.
androgen antagonists ; body composition ; contraception ; exercise ; physical fitness ; skinfold thickness ; women
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Podaci o izdanju
Povezanost rada
Kineziologija, Socijalne djelatnosti