engleski

Effects of peptid-M (LUPEX) on cellular findings and appoptosis in uveitis and retinopathy

The results indicate that cytogenetic tests are sensitive methods for the screening and detection of genome damages in human lymphocytes obtained from the subjects suffering from different ocular and other immune-mediated diseases. Peptid-M (met-enkephalin) induce modulation of the cell cycle, its cytostatic effects with the prevention of mutation and reduction of apoptosis (programmed cell death) suggest possible applications of this pentapeptide in different diseases which involved lymphocytes dysfunctions, chromosomal aberrations and/or abnormal PBL proliferation.

peptid-M; cytogenetic findings; apoptosis; uveitis; rethinopathy

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