engleski

CuTC mediated coupling of 6, 7-disubstituted benzothiazoles and cyclisation reaction tothiazole annelated benzo[c]cinnolines

New polyciclic compounds of bis-thiazolbenzo[c]cinnoline type were prepared by multistep synthesis. The key step was the formation of C-C bond between two benzothiazole moites. From several examined copper mediated aryl-aryl bond formation only method of Copper(I)-thiophene-carboxylate promoted coupling was successful. The products shown in Figure 1 were obtained from the corresponding o, o’ -disubstituted 6, 6’ - or 7, 7’ -bisbenzothiazole by the cyclisation reaction.

bis-thiazolbenzo[c]cinnoline type compounds ; multistep synthesis ; CuTC

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