Ultrasensitive Electrocatalytic DNA Detection at 3D Nanoelectrodes (CROSBI ID 108246)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Gašparac, Rahela ; Taft, J. Bradford ; Lapierre, A. Melisa ; Lazareck, Adam ; Xu, M. Jimmy ; Kelley, O. Shana
engleski
Ultrasensitive Electrocatalytic DNA Detection at 3D Nanoelectrodes
Elactrochemical DNA detection systems are an attractive approach to the development of multiplexed, high-thoroughput DNA analysis systems for clinicaland research applications. We have engineered a new class of nanoelectrode ensembles (NEEs) that constitute a useful platform for biomolecular electrochemical sensing. High-sensitivity DNA detection was achived at oligonucleotide-functionalized NEEs using a label-free electrocatalytic assay. Attomole levels of DNA were detected using the NEEs, validating the promise of nanoarchitectures for ultrasenzitive biosensing.
nanoelectrode; DNA detection; cyclic voltammetry; biosensing; electrocatalytic assay
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