An adult case of Leigh disease (CROSBI ID 108489)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Malojčić, Branko ; Brinar, Vesna ; Poser, Charles ; Djaković, Višnja
engleski
An adult case of Leigh disease
Leigh's disease is a mitochondrial disease of infancy and early childhood, and is rare in adults. Following a febrile illness, a 21-year-old woman developed ataxic paraparesis and was originally diagnosed as multiple sclerosis. Her illness progressed to somnolence and quadriparesis. The unusual MR images, the discovery of elevated blood lactate and pyruvate levels, the results of muscle biopsy and the lack of response to corticosteroid treatment, led to the correct diagnosis of Leigh disease. Initiation of a ketogenic diet resulted in a rapid partial response. She recovered sufficiently to be able to walk after 6 months.
Leigh disease; MRI; Lactate; Pyruvate; Differential diagnosis; Ketogenic diet
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o izdanju
106 (3)
2004.
237-240-x
objavljeno
0303-8467