engleski

Therapy of multiple sclerosis

Although the cause of MS is not yet known, there is a number of drugs that are able to change the natural history of the disease. The mechanism of their action is based on interference with the pathogenesis of MS mediated by T cells. Recent changes in our understanding of MS based upon better appreciation that the early phase of the disease is a critical period, along with the knowledge that axons and neurons are already damaged, that the nature of the damage process may change over time, that most disease activity is clinically inapparent, and that there are extensive microscopic abnormalities in normal-appearing brain tissue, are refining treatment approaches. Current emphasis involves early use of DMT and use of combination strategies when the response to monotherapy is suboptimal.

MS; disease modifying therapy

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