engleski

Colorectal cancer trends by age and sex distribution, anatomic subsite and survival.

Recent epidemiological studies have suggested that the anatomic distribution of colorectalcarcinoma, especially in developed countries may have undergone a distal to proximal shift over several decades, which has been attributed variously to environmental and genetics factors as well as preventive measures. The aim of the study was to compare some colorectal cancer features (age and sex distribution, anatomic localization, and survival) during fourteen years, in order to assess the possible changing trends of these disease during the observed period and to compare observed data with our previous study published in 1985 as well as with similar colorectal cancer features reported worldwide. The mean age of patients with right-sided carcinomas was slightly higher than in patients with left-sided colorectal carcinomas (65.9 vs+ 65.2). Sex distribution showed male predominance (57.3% vs. 42.7%). Males and females had similar anatomic distribution. Recto-sigmoid was the most common site (77.9%) followed by transverse colon cancers (6.8%), ascending colon cancers (6.5%), cancers in cecum (6.2%) and descending colon cancers (2.6%). In the last four years of the observed period (1999 to 2002) the incidence of right-sided cancers was increased compared to the previous period. Our study showed a continuing trend of the increased incidence of right-sided carcinomas that is similar with reports from western European countries and North America.

right-sided colorectal carcinomas; left sided colorectal carcinomas; changing trend

Rad je kao predavanje prezentiran na skupu 4th Ljudevit Jurak International Symposium on Comparative Pathology, održanom od 06.-07.06.2003.g., Zagreb, Hrvatska ; objavljen u Zborniku ; Božo Krušlin, Mladen Belicza (ur.) ; ISBN 9539701813.