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izvor podataka: crosbi

Compartmentalization of growth factor receptor signalling (CROSBI ID 112771)

Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija

Hoeller, Daniela ; Volarević, Siniša ; Đikić, Ivan Compartmentalization of growth factor receptor signalling // Current opinion in cell biology, 17 (2005), 107-111-x

Podaci o odgovornosti

Hoeller, Daniela ; Volarević, Siniša ; Đikić, Ivan

engleski

Compartmentalization of growth factor receptor signalling

Spatial and temporal separation of signal transduction pathways often determines the specificity in cellular responses. Recent advances have improved our understanding of how growth factor signalling is influenced by the formation of molecular complexes (signalosomes) in distinct cellular compartments. There has also been new insight into the mechanisms that determine the signalling competence of these complexes and their role in receptor endocytosis, retrograde trafficking in neurons and restricted protein biosynthesis, and many examples have been found where signalosome deregulation leads to disease.

Signalling; compartmentalization; growth factor receptors; ribosomes; signalling and selective translation; diseases

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Podaci o izdanju

17

2005.

107-111-x

objavljeno

0955-0674

Povezanost rada

Temeljne medicinske znanosti

Indeksiranost