engleski

Effect of metal ions on the liver nuclei

The influence of metal ions Mg (0, 1 mg/L), Pb (0, 3 mg/L) and Se (0, 1 mg/L) on liver cells of carp (Cyprinus carpio L.) was investigated during theperiod of 80 days.Already after 7 days of treatment a major increase in number of nuclei with two or three nucleoli was observed. After this initial increase oscillations followed but with a reduction tendency of nucloli number to untreated group level. Nucleolus is the place of ribosomal RNA production and is especially well developed in cells active in protein synthesis. A larger number of nucleoli suggest metal inducted increase of protein synthesis, probably connected to cells detoxication mechanism.

toxicology; magnesium; lead; selenium; nuclei; morphology

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