Chiral Chromenes: Synthesis, Separation of Enantiomers and Barriers to Racemization (CROSBI ID 113933)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Lončar, Linda ; Otočan, Klaudio ; Mintas, Mladen ; Trotsch, Thomas ; Mannschreck, Albrecht
engleski
Chiral Chromenes: Synthesis, Separation of Enantiomers and Barriers to Racemization
2H-chromenes 3 and 4 have been synthesized by reduction of the appropriate lactone with diisobutylaluminium hydride and subsequent O-alkylation of the resulting lactols. Separations or enrichments of enantiomers were achieved by liquid chromatography on triacetylcellulose and tribenzoylcellulose, (+)-3 and (-)-3 being separated almost completely, while an enrichment of the enantiomers of 4 was achieved by using the recycling procedure. The barriers for the interconversion of enantiomers of 3 and 4 were determined by thermal racemization of enantiomers.
2H-chromenes; enantiomers; separation; barriers to racemization
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano