In vivo effect of progesteron and estrogen on thymus mass and T-cell functions in female mice (CROSBI ID 114013)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Marotti, Tatjana ; Sirotković, Maja ; Pavelić, Jasminka ; Gabrilovac, Jelka ; Pavelić, Krešimir
engleski
In vivo effect of progesteron and estrogen on thymus mass and T-cell functions in female mice
Progesteron and estradiol, administered in doses equivalent to those used for therapy caused a marked transient reduction of the thymus mass, but did not affect the cellularity of other lymphoid organs. Humoral and cellular immune response of the hormone-treated mice was normal at the time of thymus involution. The same was true for the stem-cell differentiation capacity. The remaining thymus cells after hormone treatment showed increased DNA-synthesis.
progesteron ; estrogen ; thymus ; T-cell
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Podaci o izdanju
Povezanost rada
Temeljne medicinske znanosti