6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells (CROSBI ID 114141)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Grdiša, Mirica ; Kralj, Marijeta ; Eckert-Maksić, Mirjana ; Maksić, Zvonimir
engleski
6-amino-6-deoxyascorbic acid induces apoptosis in human tumor cells
6-Amino-6-deoxyascorbic acid was found to inhibit human tumor cell growth. The antitumor effect depends on the tumor type and concentration of the acid. After cell treatment with 6-amino-6-deoxyascorbic acid, drastic morphological changes were found. Although image analysis did not show a difference in p53 and c-myc gene expression, the appearance of chromatin aggregation and DNA fragmentation points to apoptosis or programmed cell death.
6-amino-6-deoxyascorbic acid ; apoptosis
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Podaci o izdanju
121 (2)
1995.
98-102
objavljeno
0171-5216
1432-1335
10.1007/BF01202220
Povezanost rada
Temeljne medicinske znanosti