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Conversion of thyroxine to triiodothyronine and reverse triiodothyronine in human placenta and fetal membranes (CROSBI ID 115372)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Banovac, Krešimir ; Bzik, Ljubica ; Tišlarić, Dubravka ; Sekso, Mladen Conversion of thyroxine to triiodothyronine and reverse triiodothyronine in human placenta and fetal membranes // Hormone research, 12 (1980), 253-259

Podaci o odgovornosti

Banovac, Krešimir ; Bzik, Ljubica ; Tišlarić, Dubravka ; Sekso, Mladen

engleski

Conversion of thyroxine to triiodothyronine and reverse triiodothyronine in human placenta and fetal membranes

Conversion of thyroxine (T4) to 3, 5, 3'- triiodothyronine (T3) and reverse 3, 3', 5'- triiodothyronine (rT3) was measured in vitro in human placenta and fetal membranes. T4 (5 mcg/ml) was incubated in 0.15 mol/l phosphate buffer with tissue homogenates for 2h at 37 C, and T3 and rT3 generated were determined in ethanol extract using RIA methods. The placenta and chorion homogenates converted more T4 to T3 than to rT3 ; the placenta was more active than the chorion. In both tissues the highest converting activity was found in microsomal fractions.

Thyroxine conversion ; Human placenta ; Chorion

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Podaci o izdanju

12

1980.

253-259

objavljeno

0301-0163

1423-0046

Povezanost rada

Temeljne medicinske znanosti

Indeksiranost