Isolation and characterisation of senescent cells from immortal human cell line MDA-MB-231 (CROSBI ID 511204)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Ćukušić, Andrea ; Ivanković, Milena ; Gotić, Ivana ; Rubelj, Ivica
engleski
Isolation and characterisation of senescent cells from immortal human cell line MDA-MB-231
Normal human somatic cells have a limited division potencial when they grow in vitro. That happens due to the shortening of telomeres. immortal cell line MDA-MB-231 has an active telomerase, which stops telomere shortening and allows permanent division.In that cell line is documentated some percentage of cells that do not divide during a few days time of growth in culture. It can be concluded that the stop of division of some cells of immortal MDA-MB-231 cell line, like in the case of some other tumor cells, is a consequense of great genomic instability.
MDA-MB-231 cells; telomerase; cell senescence; DiI
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
2005.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
Second Congress of Croatian Geneticists
poster
24.09.2005-27.09.2005
Supetar, Hrvatska