engleski

R-threshold of Quick Nystagmic component as a Measure of Central Angiopathy in the Elderly

The measurement of R-threshold of quick nystagmic component provides a source of data on the function of prepontic reticular formation, vestibule nuclei, and surrounding areas. The central nervous system myelinization and maturation lead to a decrease in the R-threshold of the quick nystagmic component. Therefore, using this parameter it is possible to obtain specific data on the subject's neural age. Previous studies have demonstrated that patients with central angiopathy have a reduced R-threshold of the quick nystagmic component. The aim of this study was to evaluate the age effect on R-threshold of quick nystagmic component. One hundred subjects aged 60-99 years were divided into two groups: a group of subjects with various risk factors for developing central angiopathy ; and a group of healthy elderly subjects. Results pointed to an age-related decrease in the R-threshold of the quick nystagmic component. Those older subject with risks for central angiopathy had a grater decrease in R-threshold than did healthy older subjects. It seems that R-threshold of quick nystagmic component can be a good predictor of premature ageing of cerebral arteries.

elektronystagmography ; nystagmus ; physiology ; central angiopathy ; ageing

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