Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives (CROSBI ID 121819)
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Podaci o odgovornosti
Merkaš, Sonja ; Litvić, Mladen ; Cepanec, Ivica ; Vinković, Vladimir
engleski
Synthesis of Novel, Potentially Biologically Active Dibenzosuberone Derivatives
Novel representatives of the important group of biologically active dibenzosuberone derivatives were prepared, 3, 7-dibromo-5-(dimethylaminoethyl-oxyimino)-10, 11-dihydro-5H-dibenzo[a, d]cyclohepta-1, 4-diene (1), 3, 7-dibromo-5-(3-dimethylaminopropylidene)-10, 11-dihydro-5H-dibenzo[a, d]cycloheptene (2) and 1, 7-dibromo-5-(3-dimethylaminopropylidene)-10, 11-dihydro-5H-dibenzo[a, d]cycloheptene (3). These compounds are potential members of tricyclic antidepressants (TCAs), still in many countries the most frequently prescribed antidepressants.
Dibenzosuberone ; tricyclic antidepressants ; bromination ; amitryptiline ; noxiptiline
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